NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which treatment is dosed every 8 hours for CF, but at least 4 hours apart?

  1. Dornase Alfa

  2. Aztreonam (Cayston)

  3. Tobramycin (TOBI)

  4. Pancrealipase

The correct answer is: Aztreonam (Cayston)

For the treatment of cystic fibrosis, it is important to carefully follow the dosing schedule to ensure the best outcomes. Dornase Alfa, Tobramycin, and Pancrealipase all need to be taken more frequently than every 8 hours, making them incorrect choices. Dornase Alfa is taken every 12 hours, Tobramycin is taken every 24 hours, and Pancrealipase is taken with every meal and snack. Choosing any of these options would result in the doses being taken too frequently or not frequently enough. Aztreonam (Cayston) is the correct choice because it is dosed every 8 hours, but at least 4 hours apart. This dosing schedule allows for a consistent and effective treatment of cystic fibrosis.