NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which medications are used for secondary prevention of ACS to reduce morbidity and mortality?

  1. Beta-blockers and ACE inhibitors

  2. Fibrinolytics and Nitroglycerin

  3. P2Y12 inhibitors and Statin

  4. Anticoagulants and Calcium Channel Blockers

The correct answer is: P2Y12 inhibitors and Statin

P2Y12 inhibitors and Statins are the most commonly used medications for secondary prevention of ACS. Beta-blockers and ACE inhibitors, while commonly prescribed for other cardiac conditions, have shown limited benefit in reducing morbidity and mortality for patients with ACS. Fibrinolytics and Nitroglycerin are typically used for acute treatment of ACS, rather than for secondary prevention. Anticoagulants and Calcium Channel Blockers may also be used in acute treatment, but have not been shown to significantly reduce morbidity and mortality in secondary prevention.