NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the recommended trough level monitoring range for Tacrolimus?

  1. 3-15 ng/mL

  2. 100-400 ng/mL

  3. 3-8 ng/mL

  4. 5-10 ng/mL

The correct answer is: 3-15 ng/mL

Tacrolimus is an immunosuppressive medication commonly used after organ transplants. The recommended trough level monitoring range for Tacrolimus is 3-15 ng/mL. This range allows healthcare providers to ensure that the drug is within therapeutic levels to prevent organ rejection while minimizing the risk of toxicity. Options B, C, and D provide monitoring ranges that are either too high or too narrow, which can lead to suboptimal treatment outcomes or an increased risk of adverse effects.