NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the first treatment approach for T2DM?

  1. Insulin

  2. Metformin + lifestyle changes

  3. DPP-4 inhibitors

  4. SGLT2 inhibitors

The correct answer is: Metformin + lifestyle changes

The first treatment approach for T2DM is usually a combination of metformin and lifestyle changes. Insulin is typically used as a second or third line treatment if the initial approach is not effective. DPP-4 inhibitors and SGLT2 inhibitors are also used as second or third line treatments, but they are not considered first line treatments. Overall, lifestyle changes, such as diet and exercise, are crucial in managing T2DM and should always be incorporated in the treatment plan.