NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is the first line treatment for Overactive Bladder (OAB)?

Anticholinergics
Beta-3 receptor agonist
Behavioral therapies
Botox injection

The correct answer is: Behavioral therapies

Behavioral therapies are considered the first-line treatment for Overactive Bladder (OAB) because they have minimal side effects compared to pharmacological treatments. Behavioral therapies may include bladder training, pelvic floor muscle exercises (Kegel exercises), fluid management, and lifestyle modifications. These therapies aim to improve bladder function by retraining the bladder and changing certain habits that may exacerbate OAB symptoms. Anticholinergics and beta-3 receptor agonists are also commonly used to treat OAB but are usually reserved for cases where behavioral therapies have not been effective or for patients who prefer pharmacological treatment. Botox injections are typically considered a third-line treatment option for OAB when other interventions have not been successful.