NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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What is a major warning for patients considering Naltrexone/Bupropion (Contrave)?

  1. May increase the risk of cataract formation

  2. May inc suicide risk in young adults/adolescents

  3. Can cause rapid weight gain

  4. Increased risk of bone fractures

The correct answer is: May inc suicide risk in young adults/adolescents

Contrave, a combination of Naltrexone and Bupropion, is commonly used as a weight loss medication. However, one major warning for patients considering this medication is that it may increase the risk of suicide in young adults and adolescents. This is why it is important for patients to be closely monitored while taking this medication and to immediately report any changes in mood or behavior to their doctor. Option A, cataract formation, is not a commonly reported side effect of Contrave. Option C, rapid weight gain, is the opposite effect of what this medication is intended for and is not listed as a potential warning. Option D, increased risk of bone fractures, may occur with long-term use of Bupropion but is not listed as a major warning specifically for Contrave. However, patients should still discuss any potential risks with their doctor before starting this medication.