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Clozapine (Clozaril) is an atypical antipsychotic medication that is associated with a rare but serious side effect known as agranulocytosis, which is a severe reduction in the number of white blood cells, specifically neutrophils. Monitoring the Absolute Neutrophil Count (ANC) is crucial for patients taking clozapine to detect any early signs of agranulocytosis. Regular monitoring of ANC levels allows for prompt detection of low neutrophil counts, which can help prevent severe infections and other complications. Therefore, option B is the correct choice for monitoring parameters in patients taking clozapine.

Options A, C, and D are not directly required to be monitored specifically for patients taking clozapine. While renal function, liver enzymes, and blood glucose levels may be important to monitor for other reasons or with other medications, they are not the primary parameters to monitor when a patient is prescribed clozapine.