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Colon cancer screening is generally recommended to start at the age of 45 years. This is because most cases of colon cancer are diagnosed in individuals over the age of 50; however, recent guidelines have suggested starting screening even earlier at 45 due to the increasing incidence of colon cancer in younger individuals. Starting screening at 45 allows for the early detection and treatment of colon cancer, ultimately improving outcomes and reducing mortality rates. Starting screening at an earlier age can help detect precancerous lesions or early-stage cancers before they progress, making it a crucial preventive measure in managing colon cancer.