NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which substance is known to cause Pulmonary Arterial Hypertension?

  1. Caffeine

  2. Nicotine

  3. Cocaine

  4. Alcohol

The correct answer is: Cocaine

Cocaine is known to cause Pulmonary Arterial Hypertension. Cocaine use can lead to vasoconstriction and vascular remodeling in the pulmonary arteries, ultimately resulting in increased pulmonary artery pressures. This can lead to the development of Pulmonary Arterial Hypertension over time. Among the other options: - A. Caffeine is a stimulant, but it is not directly linked to causing Pulmonary Arterial Hypertension. - B. Nicotine, found in tobacco products, can lead to various cardiovascular issues, but it is not typically associated with causing Pulmonary Arterial Hypertension. - D. Alcohol abuse can lead to several health issues, but it is not a known direct cause of Pulmonary Arterial Hypertension.

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