NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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For severe hypophosphatemia, what is the recommended mode of replacement?

Oral supplementation
Dietary adjustment
IV replacement
Subcutaneous injection

The correct answer is: IV replacement

Severe hypophosphatemia is a condition where the levels of phosphorus in the blood are significantly low. In this case, immediate and effective replacement is necessary in order to prevent serious complications. While oral supplementation and dietary adjustments may be effective for mild cases of hypophosphatemia, in the case of severe hypophosphatemia, these methods may not provide a quick and adequate supply of phosphorus to the body. Similarly, subcutaneous injection may not be a suitable option as it may not be able to provide a sufficient amount of phosphorus in a timely manner. IV replacement, on the other hand, delivers phosphorus directly into the bloodstream, ensuring that the body gets an adequate and immediate supply of this essential mineral. Therefore, IV replacement is the recommended mode of replacement for severe hypophosphatemia.